CDC IIS: Programmatic and Technical Contact List Update

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Updates to ACIP General Best Practice Guidelines

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The following changes were made to the ACIP Best Practice Guidelines for Immunization in July 2017

Table 3-1. (Recommended and minimum ages and intervals between vaccine doses)

  • Footnote f has been clarified:
    It now reads, “The minimum recommended interval between DTaP-3 and DTaP-4 is 6 months. However, DTaP-4 need not be repeated if administered at least 4 months after DTaP-3. This is a special grace period of 2 months which can be used if evaluating records retrospectively. An additional 4 days cannot be added to this grace period prospectively, but can be added retrospectively.”

    This change is to accommodate a recent subject-matter expert email that allows double dipping of the grace period (adding 4 days to the 2 months) for retrospective validation of series WHOSE 4th DOSE WAS ADMINISTERED AT 12 months of age. This double dipping cannot be applied prospectively, meaning we will only allow a 4 day grace period added to a prospective 6 month interval, and we will only allow a four month interval prospectively (not four months plus four days) if the fourth dose would be administered after 12 months of age. CDSi has been updated to accommodate this.

TABLE 4-1. (Contraindications and precautions to commonly used vaccines)

  • Added to LAIV contraindications: “LAIV4 should not be administered to persons who have taken influenza antivirals medications within the previous 48 hours.” This addition is to harmonize this table with the 2017-18 adult schedule.
  • Serogroup B meningococcal vaccine has been added to the table.
  • Added to MMR and Varicella contraindications: “Family history of altered immunocompetence.” To harmonize with the vaccine-specific statements in accommodating infants and toddlers with occult heritable congenital immunodeficiencies.
  • Added to Varicella and Zoster precautions: “Receipt of specific antiviral drugs (acyclovir, famiciclovir, or valacyclovir) 24 hours before vaccination (avoid use of these antiviral drugs for 14 days after vaccination).”
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CDC News: Immunization MMWRs Update

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This message serves to inform you that one or more MMWRs have recently been added to the MMWR page and are now available.

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Register now – Aging & the Immune System: Rethinking Vaccines for Older Adults

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The immune system changes with age—making it more difficult for older adults to fight off infections and reducing their response to vaccines. New research on how the immune system changes is already improving the effectiveness of vaccines for older adults and making progress toward ensuring longer, healthier lives for all Americans.

Tuesday, Sept. 26 from 12pm-1pm ET, join the National Vaccine Program Office (NVPO) and Centers for Disease Control and Prevention (CDC) for the webinar, Aging & the Immune System: Rethinking Vaccines for Older Adults.

Register now

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What’s New at CBER Update

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What’s New at CBER

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What’s New at CBER Update

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What’s New at CBER Update